Synthetic Multi-Plate Bead Assay Example Dataset

A synthetic dataset that mirrors the structure expected by fit_calibration_freq_multiplate(). Contains two antigens (alpha and beta) across three replicate plates each (six curve_ids total).

A synthetic dataset that mirrors the structure expected by fit_calibration_freq_multiplate(). Contains two antigens (alpha and beta) across three replicate plates each (six curve_ids total).

Format

A list with six elements:

standards

Data frame, 60 rows. One row per standard well.

blanks

Data frame, 24 rows. Four blank wells per plate.

samples

Data frame, 120 rows. Patient samples at dilution 1:2000.

curve_id_lookup

Data frame, 6 rows. Maps curve_id to antigen/plate.

response_var

Character. Name of the response column ("mfi").

indep_var

Character. Name of the independent variable ("concentration").

A list with six elements:

standards

Data frame, 60 rows. One row per standard well.

blanks

Data frame, 24 rows. Four blank wells per plate.

samples

Data frame, 120 rows. Patient samples at dilution 1:2000.

curve_id_lookup

Data frame, 6 rows. Maps curve_id to antigen/plate.

response_var

Character. Name of the response column ("mfi").

indep_var

Character. Name of the independent variable ("concentration").

Source

Synthetic data generated for package documentation.

Synthetic data generated for package documentation.

Details

The alpha curves were simulated with a Gompertz model; the beta curves with a 5PL model, reflecting realistic between-antigen variation in curve shape.

The alpha curves were simulated with a Gompertz model; the beta curves with a 5PL model, reflecting realistic between-antigen variation in curve shape.